What Is SLU-PP-332?
SLU-PP-332 is a synthetic small molecule that activates all three estrogen-related receptors: ERR alpha, ERR beta and ERR gamma. The compound series was developed by research groups in St. Louis, Missouri, including chemists at Saint Louis University, with key studies published from 2023 onward. Despite the similar name, the ERRs are not estrogen receptors and are not activated by estrogen. They are nuclear receptors that control genes involved in mitochondrial energy production and fatty acid use.
Many suppliers list it as the "SLU PP 332 peptide", and it is sold alongside research peptides, but it is not a peptide. It is a small organic molecule with no amino acid chain. That matters in the lab: it behaves differently from a peptide in solution, and it is one of the few compounds in this field that can be supplied in a solid oral format as well as a vial.
What Does SLU-PP-332 Do?
The estrogen-related receptors act as switches for the energy-producing machinery of the cell. When SLU-PP-332 activates them, genes for mitochondrial biogenesis, oxidative metabolism and fatty acid oxidation are switched on, the same programme that endurance exercise induces in muscle. That is why SLU-PP-332 is described as an exercise mimetic, and why it is studied in models of metabolism, muscle and organ ageing.
- ERR alpha. The main regulator of mitochondrial biogenesis and energy metabolism; much of the exercise-like response in published work depends on it.
- ERR beta and gamma. Expressed in energy-demanding tissues such as heart, kidney and muscle.
SLU-PP-332 Research
The published research on SLU-PP-332 is preclinical, carried out mainly in mice and cell models. Studies have examined its effects on exercise capacity, metabolic syndrome, heart failure and mitochondrial function in the ageing kidney, and newer work has introduced a successor compound, SLU-PP-915. It also appears in anti-doping research, where laboratories have characterised its metabolites for detection. Browse the citations, with links to each paper, in our SLU-PP-332 research library.
SLU-PP-332 5mg Vial: Powder for Reconstitution
The SLU-PP-332 5mg vial holds the compound as a freeze-dried powder, sealed in a 3 mL clear glass vial under a rubber stopper and flip-off cap. Supplying it dry keeps it stable in storage and in transit, and it lets you set the concentration you work at rather than accepting a fixed one. The label carries the strength, lot number and expiry, and the lot links to its certificate of analysis.
To reconstitute SLU-PP-332 powder, add a suitable sterile diluent such as bacteriostatic water slowly down the inside wall of the vial and swirl gently until it has fully dissolved. Keep the vial at 2 to 8 °C, protected from light, and use it within 28 days of mixing. The vial suits laboratory and in vitro work that needs the compound in solution, and our reconstitution guide and calculator covers the steps for any fill size.
SLU-PP-332 Capsules
SLU-PP-332 capsules contain 250mcg each and come in a 60-count bottle with a white child-resistant cap. Because SLU-PP-332 is a small molecule rather than a peptide, it stays stable as a dry solid, and that is what makes a capsule format possible at all; most compounds in this field are supplied only as lyophilized vials. The capsules are the format people are usually looking for when they search for SLU-PP-332 tablets or pills.
The capsule format needs no preparation: there is nothing to reconstitute and no diluent to measure, and each capsule holds a fixed, pre-measured amount. Store the bottle closed, below 25 °C and somewhere dry and dark, since moisture is the main thing that degrades a solid format. Every capsule lot is tested by an independent laboratory for identity and purity, and its lot number matches the certificate on our COA lookup page.
SLU-PP-332 Vial or Capsules: Which Format?
| 5mg vial | Capsules | |
|---|---|---|
| Form | Lyophilized (freeze-dried) powder | Pre-measured solid capsules |
| Container | 3 mL glass vial, flip-off cap | Capsule bottle, child-resistant cap |
| Preparation | Reconstitute before use | None |
| Storage | 2 to 8 °C, protect from light | Below 25 °C, dry, away from light |
| Suits | Custom concentrations in solution | Designs that use a fixed solid format |
Our recommendation: choose the vial when your work needs the compound in solution at a concentration you set, and the capsules when a pre-measured solid format fits the study design.
SLU-PP-332 vs 5-Amino-1MQ and Retatrutide
| Compound | Type | Primary target |
|---|---|---|
| SLU-PP-332 | Small molecule | ERR alpha, beta and gamma (nuclear receptors) |
| 5-Amino-1MQ | Small molecule | The NNMT enzyme |
| MOTS-c | Mitochondrial-derived peptide | Encoded in mitochondrial DNA |
| Retatrutide | Peptide | GIP, GLP-1 and glucagon receptors |
SLU-PP-332 and 5-Amino-1MQ are both small molecules studied in energy metabolism, but one works through nuclear receptors and the other through an enzyme, so researchers often run them side by side. Retatrutide acts on hormone receptors at the cell surface, an entirely different route. See all mitochondrial research compounds.
Buy SLU-PP-332 Online in Australia
Chainwell Peptide supplies SLU-PP-332 for sale in Australia to laboratories and independent researchers. Before you buy SLU-PP-332 online from any supplier, check the format and fill are stated clearly, the product carries a lot number, and the certificate of analysis for that lot is available. Ours can be checked on the COA lookup page.
- Same-day dispatch on orders paid before 3pm AEST on a business day.
- Australia-wide delivery by standard or express post, to Perth, Adelaide, Brisbane, Sydney, Melbourne, Hobart and regional postcodes.
- PayID or bank transfer, with your order number as the payment reference.
The current price for each format is shown at the top of this page, with GST included, and shipping is charged once per order.
SLU-PP-332 Specifications
| Compound | SLU-PP-332 |
|---|---|
| Class | Synthetic small-molecule pan-ERR agonist (not a peptide) |
| Targets | Estrogen-related receptors alpha, beta and gamma |
| Formats | 5mg lyophilized vial; 250mcg capsules, 60-count bottle |
| Label | Product, format, lot number, expiry, research-use statement |
| Testing | Identity and purity by an independent laboratory, per lot |
| Shipping | Standard or express post, Australia-wide |
Research Use Only
SLU-PP-332 is a research compound. It is not approved by the Therapeutic Goods Administration for any therapeutic use, and Chainwell Peptide sells it strictly for laboratory and in vitro research, in both vial and capsule form. It is not for human or veterinary use, and we do not provide dosing advice. By ordering you agree to our terms and conditions and research use only statement.
SLU-PP-332 tools and guides
SLU-PP-332 FAQ
What is SLU-PP-332?
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SLU-PP-332 is a synthetic small molecule that activates the estrogen-related receptors ERR alpha, beta and gamma, nuclear receptors that control mitochondrial energy metabolism. It is studied as an exercise mimetic in preclinical research. Chainwell Peptide supplies it as a 5mg lyophilized vial or in capsules.
Is SLU-PP-332 a peptide?
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No. SLU-PP-332 is often sold alongside research peptides and described as a peptide, but it is a small organic molecule with no amino acid chain. That is also why it can be supplied as capsules as well as a lyophilized vial, which is unusual for compounds in this field.
What does SLU-PP-332 do?
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SLU-PP-332 activates the estrogen-related receptors, which switch on genes for mitochondrial biogenesis, oxidative metabolism and fatty acid oxidation. This is the same cellular programme endurance exercise triggers in muscle, which is why the compound is called an exercise mimetic in preclinical studies.
Should I choose the SLU-PP-332 vial or the capsules?
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Choose the 5mg vial when your work needs SLU-PP-332 in solution at a concentration you set; it is reconstituted before use and stored at 2 to 8 °C. Choose the capsules when your study design uses a pre-measured solid format. Both come with a lot-matched certificate of analysis.
Where can I buy SLU-PP-332 online in Australia?
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You can buy SLU-PP-332 online in Australia from Chainwell Peptide, as a 5mg vial or in capsules. Each lot carries a lot number matched to an independent certificate of analysis, and orders paid before 3pm on a business day ship the same day by standard or express post.
